San Francisco 49ers: 2025 NFL Schedule
Below you will find the weekly regular-season schedule for the San Francisco 49ers.
| Week | Date | Opponent | Results |
|---|---|---|---|
| Week 1 | Sun., Sept. 7 | at Seattle Seahawks | W 17-13 |
| Week 2 | Sun., Sept. 14 | at New Orleans Saints | W 26-21 |
| Week 3 | Sun., Sept. 21 | vs. Arizona Cardinals | W 16-15 |
| Week 4 | Sun., Sept. 28 | vs. Jacksonville Jaguars | L 26-21 |
| Week 5 | Thu., Oct. 2 | at Los Angeles Rams | W 26-23 (OT) |
| Week 6 | Sun., Oct. 12 | at Tampa Bay Buccaneers | L 30-19 |
| Week 7 | Sun., Oct. 19 | vs. Atlanta Falcons | W 20-10 |
| Week 8 | Sun., Oct. 26 | at Houston Texans | L 26-15 |
| Week 9 | Sun., Nov. 2 | at New York Giants | W 34-24 |
| Week 10 | Sun., Nov. 9 | vs. Los Angeles Rams | L 42-26 |
| Week 11 | Sun., Nov. 16 | at Arizona Cardinals | W 41-22 |
| Week 12 | Mon., Nov. 24 | vs. Carolina Panthers | W 20-9 |
| Week 13 | Sun., Nov. 30 | at Cleveland Browns | W 26-8 |
| Week 14 | BYE | ||
| Week 15 | Sun., Dec. 14 | vs. Tennessee Titans | W 37-24 |
| Week 16 | Mon., Dec. 22 | at Indianapolis Colts | W 48-27 |
| Week 17 | Sun., Dec. 28 | vs. Chicago Bears | W 42-38 |
| Week 18 | Sat., Jan. 3 | vs. Seattle Seahawks | L 13-3 |
Past 49ers results: 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015
Also, check out the following resources: