San Francisco 49ers: 2022 NFL Schedule
Below you will find the weekly regular-season schedule for the San Francisco 49ers.
| Week | Date | Opponent | Time (ET) / Tickets |
|---|---|---|---|
| Week 1 | Sun., Sept. 11 | at Chicago Bears | L 10-19 |
| Week 2 | Sun., Sept. 18 | vs. Seattle Seahawks | W 27-7 |
| Week 3 | Sun., Sept. 25 | at Denver Broncos | L 10-11 |
| Week 4 | Mon., Oct. 3 | vs. Los Angeles Rams | W 24-9 |
| Week 5 | Sun., Oct. 9 | at Carolina Panthers | W 37-15 |
| Week 6 | Sun., Oct. 16 | at Atlanta Falcons | L 14-28 |
| Week 7 | Sun., Oct. 23 | vs. Kansas City Chiefs | 4:25 PM / Tickets |
| Week 8 | Sun., Oct. 30 | at Los Angeles Rams | 4:25 PM / Tickets |
| Week 9 | BYE | ||
| Week 10 | Sun., Nov. 13 | vs. Los Angeles Chargers | 8:20 PM / Tickets |
| Week 11 | Mon., Nov. 21 | at Arizona Cardinals | 8:15 PM / Tickets |
| Week 12 | Sun., Nov. 27 | vs. New Orleans Saints | 4:25 PM / Tickets |
| Week 13 | Sun., Dec. 4 | vs. Miami Dolphins | 4:05 PM / Tickets |
| Week 14 | Sun., Dec. 11 | vs. Tampa Bay Buccaneers | 4:25 PM / Tickets |
| Week 15 | Thu., Dec. 15 | at Seattle Seahawks | 8:15 PM / Tickets |
| Week 16 | Sat. Dec. 24 | vs. Washington Commanders | 4:05 PM / Tickets |
| Week 17 | Sun., Jan. 1 | at Las Vegas Raiders | 4:05 PM / Tickets |
| Week 18 | Jan. 7 or Jan. 8 | vs. Arizona Cardinals | TBD / Tickets |
Past 49ers results: 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010
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